Electrospun Fibers Control Drug Delivery for Tissue Regeneration and Cancer Therapy

Abstract Versatile strategies have been developed to construct electrospun fiber-based drug delivery systems for tissue regeneration and cancer therapy. We first introduce the construction of fiber scaffolds their various structures, as well commonly used types drugs. Then, we discuss some representative controlling by fibers, with specific emphasis on design endogenous external stimuli-responsive systems. Afterwards, summarize recent progress engineering, including soft engineering (such skin, nerve, cardiac repair) hard bone, cartilage, musculoskeletal systems), Furthermore, provide future development directions challenges facing use fibers controlled delivery, aiming insights perspectives smart platforms improve clinical therapeutic effects in Graphical abstract